@beccabecca it's so frustrating isn't it. At the early stages of diagnosis and treatment I was angry all the time because I believed the medical team so-called was keeping information from me deliberately but I have reached the conclusion they just don't know the answers to our most compelling questions. Everyone chants "everyone is different" but really the random way research gets done in this field means the kind of questions you are asking cannot be accurately answered. BC is one of the most mysterious and complex of diseases. The disconnect between scientific research in the lab, clinical work and epidemiology is profound. Predictive tools have come a long way and will get better but it is still almost impossible to get an estimate of rate of recurrence or time to metastases for different cancer variants at different stages. The models being used are not up to it. But I have stopped being angry and upset, at least it's nothing personal and we are all in the same boat. Warm wishes to you, A.