The needles didn't really hurt that much and to their credit they did get a new needle out each time so they weren't using blunt ones. I was just happy they found a vein and didn't have to go slicing me to find a vein for one more lousy chemo. I have a high pain threshold for needles which does help. Tip - big vein and the chemo liquids don't hurt. Piddly little hand vein and you can bet it will hurt. The last one was a hand vein and the stuff escaped into my hand and caused a chemical burn that only just healed 3 weeks later. Although dangerous to use the elbow vein as it can escape up in to the muscle above, as long as I kept my elbow locked in the open position we were goodo. It was a breeze.