Hormone treatments, tamoxifen and tendonitis
Hi there, I'm very new to this, but wondering if anyone has experience of tamoxifen and tendonitis? I've had two different types of breast cancer, but one side was HER2Positive so since January this year I have been on anastrozole. In late July I got extremely painful tendon damage - a torn and swollen hamstring tendon near my seatbone, so it really hurts to sit, and two other gluteal tendons with tendinopathy as well - no idea what set these problems off, but discovered that anastrozole, in reducing oestrogen, weakens tendons. My Oncologist said suspend it, so I haven't been taking it since early August. She later offered me a script for Tamoxifen instead. As Tamoxifen also is designed to reduce oestrogen I am wondering whether I should switch to it or not? I don't want a breast cancer recurrence, but my life quality at the moment is much affected by the tendon problem which is not healing very quickly at all. It's going to take many many months I think. If I take tamoxifen now will I slow down the healing? What should I do? Anyone out there had any experience with tamoxifen and tendons? Thanks for any experience you can share with me!!!
Three dimensional tissue engineering with biodegradable breast scaffolds post mastectomy
Hello all, The above is being researched by Queensland University Hospital with Prof Dietmar Hutmacher as the head. It will be a great alternative to breast implants as it replaced by regenerating tissue rather than replacing it. I am wondering if anyone is in the know about upcoming clinical trials? I noticed it in a couple of stories in daily newspaper and media, six years ago when I had my mastectomy and sentinal lobe clearance. I was hopeful when I saw it and held off having any of the current recon. surgeries. All the best and it's onwards and upwards, Maria
Blood test to replace mammo
Has anyone else heard or read about this? A research centre in England have successfully detected breast cancer using blood tests earlier than a mammogram would. They are currently doing further trials. How awesome would that be! I wonder if it will also detect metastatic. The blood test can apparently detect it up to five years before any symptoms appear. I am thinking the mammogram centres will try to block these trials ever coming to Australia. Oops, that is probably not a nice thing to say.
Radiotherapy side effects apart from tiredness ? Any one experienced them?
Hello everyone, I'm sorry if this question has already been asked, I've been reading many information from here as well as in other places etc, I've now had my surgery on the 27th Jan 2023, it was a lumpectomy, and it all went well, for that I'm very grateful to my surgical team, my surgeon is a fantastic woman along with her team of dr's under her, I would highly recommend them to anyone here in Brisbane. My margins were clear, along with the lymph nodes they also removed, I'm now facing this radiotherapy and have had my 1st appointment with the oncology doctor who went through everything, But these side effects are just not sitting well with me at all, I'm not to worried about the tiredness, everyone has spoken about this, and I'm still suffering with long covid as well, plus possibly post surgery recovery, I've started back with exercising, yoga and swimming. the wounds have healed nicely, and the post surgery infection and fluid build up has gone after a brief stay back in hospital 6 days later from the original surgery of the removal of the tuma & lymph nodes. Its the damage (possible) as I'm told to my ribs. the lungs and maybe the heart. and these permeant dots you get branded with like I'm live stock not a human. this has me truly upset and very stressed and concerned for my on going health, as this can and will effect my bones, and organs, Has any one has side effects to their ribs where they are sore after this treatment, or developed scaring on the lungs (that I'm also told is a possibility) My Dr (radiology oncology) did say I could get sore around the rib area, they say I need 3 weeks and 1 day's worth of this treatment, at 5 days a weeks so 16 sessions all up, Has anyone had a shorter time as I've read it can range from 2-5 weeks? Has anyone seek a second opinion or tried alternative measures? I'm extremely worried, stressed , and concerned for my health in the long run with bring subject to this now I have all these facts on what the side effects are, As I have clear margins and nodes and it seems a bit much to me. seeking your thoughts please, I'm a little fragile and extremely overwhelmed , this cancer journey sux - and like ( I would think all of us,) "I / we just want my/ our life back" as this is a nightmare that is screwing up my household and my life Thanks for reading my babble :smile:Targeted clinical trial for patients with lymphoedema related to breast cancer surgery
Hi members, The below clinical trial conducted by LeapCure may be of interest to some of you. If you have breast cancer surgery related lymphoedema following a dissection or biopsy procedure, you could be eligible to join a clinical trial that is enrolling nearby. Initial eligibility includes lymphoedema patients who have had surgery for their breast cancer at least 6 months ago and diagnosed with lymphoedema within the past 4 years. The following pre-screener will help you determine your suitability, match you to a nearby trial site, and enter you on to a list for the LeapCure team to give you a call back. To help you determine if you are eligible for the study, LeapCure, who are administering the recruitment of this study in Australia, have developed a survey found at the link below. By taking this survey, you are providing your consent (agreement) for LeapCure to collect and store your survey answers on an overseas server (large computer) that is compliant with the Health Insurance Portability and Accountability Act (USA). Here is the pre-screening link: https://research.leapcure.com/studies/bclymph?locale=en-AU&utm_source=BCNA&utm_medium=mixed&utm_campaign=060921Pv22&utm_cat=PAGNWAU&utm_study=bclymphBreast cancer treatment researcher awarded Prime Minister’s Prize for Science
The Peter MacCallum Cancer Centre’s Professor Sherene Loi has been awarded a Prime Minister’s Prize for Science for her research into innovative treatments to improve the survival of breast cancer patients. Click on the below link for the full coverage: https://www.skynews.com.au/lifestyle/health/breast-cancer-treatment-researcher-awarded-prime-ministers-prize-for-science/video/988424ceb2b4596fd15ac51d67584962
UK trial
A trial is being conducted in the UK using aspirin as part of treatment for triple negative breast cancer. The article emphasises the trial and methodology is still at an early stage and people should NOT start using aspirin themselves! Trial lead Dr Anne Armstrong said: "Not all breast cancers respond well to immunotherapy. "Trialling the use of a drug like aspirin is exciting because it is so widely available and inexpensive to produce. "We hope our trial will show that, when combined with immunotherapy, aspirin can enhance its effects and may ultimately provide a safe new way to treat breast cancer." Co-researcher Dr Rebecca Lee said their lab findings suggested that aspirin can make certain types of immunotherapy more effective by preventing the cancer from making substances that weaken the immune response. "We hope aspirin can dampen down bad inflammation so the immune system can get on with the job of killing cancer cells," she said.Trojan horse
Researchers have successfully tested a “Trojan Horse” drug which can kill cancer and bacterial cells without damaging nearby healthy tissue. Scientists at the University of Edinburgh combined the tiny cancer-killing molecule SeNBD with a chemical food compound to trick malignant cells into ingesting it. The peer-reviewed experimental study was carried out on zebrafish and human cells, but researchers say more studies are needed to confirm if it is a safe and swift method of treating early stage cancer and drug-resistant bacteria. Early days but interesting!Beta Blockers may have additional benefit
I’ll try and find more on this but from this morning’s news: Australian researchers have made a major medical breakthrough that could extend the lives of people battling breast cancer. Scientists at Monash University have found that everyday anti-stress drugs, called beta blockers, could slow the spread of the deadly disease in the body
