Newly Diagnosed - Letrozole
Moderator moved @krisol comment to new discussion post in Newly Diagnosed: krisol NSW Member Posts: 1 May 16 Hi everyone, I’m new here. im started letrozole 1 month ago and I have middle joint pain specially in the mornings. I found that exercises help me a lot and I hope long term does not affects my bones. I hope will improve with the days until my body accept this medicine. Blessings for every one.
Unsure about radiation and scared about endocrine therapy, Abemaciclib in particular!
Hi all, I am 40 years old. I had a skin and nipple sparing mastectory on 27 Nov and then further surgery on 4 Dec after my testing revealed a much big mass than expected. My nipple, additional skin and part of the breast capsule was taken - no cancer in any. I was diagnosed with multifocal cancer. Largest mass 5.4 cms. Grade 1. 4 lymph nodes taken which were all clear. ER and PR positive. LVI - nil. KI67% - 1%. I have seen an Oncologist and Radiation Oncologist this week and was also presented to the breast cancer panel a couple of weeks ago. Recommendations are possible chemo and radiation. I have done Onka Type testing and waiting on results. I have questions in relation to: - Radiation - to do or not to do; - Hormone therapy - people's experience and whether to do everything recommended. 1. Radiation Recommendations were on the fence for radiation and I have been told it is my decision, they cannot really recommend one way or another. On the one hand mass greater than 5 cms and my age, on the other, all lymph nodes clear and all good markers, given the additional surgery we have really good clearance margins, plus I will be doing hormone therapy. The risk of secondary cancer from the radiation is scary, I am not sure about the indicators all seem pretty good save for the size. If the Onka type testing shows a low % chance or recurrence I am not sure it is a risk worth taking and putting myself through that when I also have what seems like a quiet aggressive hormone therapy plan. 2. Hormone therapy My Oncologist has recommended - Letrozole for 5-10 years, Goserelin injections monthly for 5 years and Abemaciclib for 2 years. The list of all of the possible side effects from these drugs and the length of time I will be on them is probably the thing I have found most difficult to process/face to date. The Abemaciclib in particular. I was advised this is not yet on the PBS in Aust but we can get access on passionate grounds. The potential side effects with this one seem so serious and I am nervous that it seems it has not been used widely in Aust. Given all of the markers of my cancer, save for size, were all so positive I am uncertain about it. If anyone has experience with any of these treatments and could share I would really appreciate it.
Arrival
Hello, I've been in cancerland for 3 months officially. I have Invasive Lobular Breast Carcinoma in one breast with no lymph node diagnosis. I'm 77 and never imagined that this would happen - thought all those risks were done with. After 3 months of being pretty stunned I'm now encountering grief, annoyance and fear. I've been on Letrozole and take Vit D3/Calcium. The side effects have been more than unpleasant but have eased a great deal since I changed the brand to one with the least possible 'fillers' (I have allergies to 'fillers' which I'd been too brain-fogged to realise/recall that I would be stepping into a world of pain/nausea/vision problems etc etc - stupid of me). I'm prepared to keep going now as within a day I began to come out of the twilight zone - test soon to see if 'it' is shrinking. I think the worst of it is the isolation - not wanting to burden family and friends. So I took the step and that is why I'm gratefully here -
Hormone Therapy options for young women who hope to have children
Hi everyone 😊 I’m seeking some advice on what hormone therapy is best for younger women who want kids in the future. I have Grade 1 multifocal IDC+DCIS, 80% hormone positive, ER- cancer & I’m premenopausal, with no children. I was told after 2 years of hormone therapy I can try to fall pregnant (…but am hoping 1.5 will be enough?) I have been given three options for hormone therapy: •Tamoxifen only •Zoladex + Tamoxifen •Zoladex + Exemestane (Aromasin) All offer similar coverage in regards to my type of cancer, but I was wondering if there are any differences in regards to future fertility? ie. longer detox periods required before falling pregnant, or potential fertility issues after long term use, eg Zoladex or Exemestane? I have also read that Exemestane (Aromasin) is an *irreversible* steroidal aromatase inhibitor. I don’t want to be on anything that could irreversibly damage my oestrogen production.. Fertility-wise, does anyone know if this is something to avoid until after having children? I’d really appreciate any advice & tips for having the best chance of getting pregnant in 2 years! X
