Xanthelasma and raised cholesterol on letrozole.
Triple pos IDC girl here. I’m post 5 mths chemo, single mastectomy with lymph sweep with clear margins and post oopherectomy. Finished trastuzimab a bit early due to side effects so now plan is for just hormone therapy 5 yrs. I just saw GP today regarding what looks like xanthelomas. Hes given me blood form to check cholesterol and thyroid. I showed oncologist yellow skin 2 mths ago and again 5 days ago and she saying it’s not related to any cancer treatment and see GP. I looked up Letrozole info on eviQ and it states that raised cholesterol a known side effect and that levels will be monitored. Today I’ve just got results back and LDL is 5.9 and total cholesterol is 8.2. I’m starting to lose trust in oncologist and feel like I’ve got to check everything so to prevent medical harm. I do t have medical training but do have a keen interest in reading full info of every medical intervention due to previous experiences with medical system. Anyone else have cholesterol issue on letrozole? And if so did you switch to diff AI? Or did you stop taking? Or did you treat naturally? EviQ says other AI’s can all raise cholesterol too.
Letrozole - aches and pains continue
Last year I was switched from Tamoxifen to Letrozole. At first I was feeling okay on the Letrozole but then I had a post menopausal heavy bleed (thats a whole other story), so had a medication holiday. When I resumed the Letrozole I started to ache and have body pains constantly, usually at night which resulted in ongoing fatigue. I saw my doctor who advised to stop taking the Letrozole - I was 4 years post breast cancer at this stage, so it was felt, as my initial prognosis was good, this would be okay. My issue is now, 6 weeks after ceasing the Letrozole, I still get the body aches and pains. It seems to be getting slightly worse. Does anyone have any experience of ceasing the meds and how long does it take to start feeling pain free?
Zoladex
Hi, so I’ve just been started on zoladex and I’m wondering about side effects. I feel like I suddenly have IBS or something. I’m going to the toilet 5-6 times a day. Everything I eat is giving me stomach cramping, almost like continuous period pains. I also feel nauseous a lot. Is this normal? Has anyone else experienced this? Does it calm down after a while? I’m scared to start taking the letrezol as well now in case it all gets worse. I was sent home from work today, first day back, because I was doubled over in pain from the cramping. It’s ruining my life and it’s only been 2 weeks.
Letrozole - compound pharmacy
Hello I was wondering if anyone has had any luck with getting Letrozole made by a compounding pharmacy to reduce the fillers and preservatives that come with the commercial Letrozole? I am about to start Letrozole and am trying to minimise side-effects as much as possible from the get-go to increase my chances of staying on it - I am very sensitive to meds, preservatives, etc. With that in mind, I’m very interested in hearing people’s stories and experiences with compounding chemists and hormone therapy. Thank you all :)
Potential liver issue
Triple positive Radiation and chemo AC and paclitaxol completed by March 2024 Lumpectomy Feb Early stage On letrozole, zoladex and finishing of my 17th cycle end November of Herceptin. Also taking 5mg of cholesterol tabs. Gp rwq blood to monitor the cholesterol tabs and if they working. Liver issue picked up. Oncologist req abdomen scan. Been feeling ok but for the last two days terrible nausea after eating. Headaches (which I never get) fatigue (which has also been ok) Has anyone been through something similar, what was the outcome? Look forward to hearing from you x
Total left mastectomy vs expander/implant?
Hi everyone - I’m newly diagnosed and have found BCN hugely helpful and reassuring. I have bilateral early cancers - invasive ductal (left side) and invasive lobular (right side). ER + PR + HER2 -.I believe ‘low grade, slow growing’. My treatment recommendation is: left side mastectomy, nipple/skin sparing with expander then later implant and right side lumpectomy. Followed by radiation and letrozole. Surgery scheduled for 22/11 at Chris O’Brien Lifehouse. The choice I have is left side total mastectomy or the reconstruction? For context, I’m middle aged, slim/small breasted and physically very active. Apart from the obvious surgery and post operative worries, my other concern is around the possibility of spending many months with ongoing breast related issues. Wondering if any of you have had a similar experience….and any thoughts/advice you might have? Thank you 🎀
Letrozole aches and pains
Hi everyone, I hope everyone is having a good day today :) I was put on Tamoxifin in March after my BC treatment, and then I found I had PALB2 so I had an oophorectomy and my Onc changed my meds to Letrozole now I have no ovaries. My sister in-law is a naturopath and kinesiologist and after all my chemo and radio she tested me and gave me a herb concoction to "clean up the mess". I told her what ever she gives me needs to be hormone free and compliment Letrozole, she has treated many cancer patients before and said all is ok. So, I was feeling ok, well, as ok as you can be for being put into chemical menopause, you know, hot flashes, a few aches and pains, brain fog.. hmmm maybe a bit more than a fog :) not great but I was managing, so my Onc says she isn't happy with me being on the herbs, she cannot know if they are still giving me hormones (or what ever it does) so she told me to stop, she said my body basically needs to go cold turkey on hormones and she needs to be sure nothing is effecting my medication. So, I went off them straight away and literally a week later....hoolie doolie I feel like I've been hit by a truck! My aches and pains in my back, legs, elbows, shoulder, neck are horrible, my legs have that tight tense feeling like they are just about to cramp...all the time! Sleeping is almost impossible, either waking up and staying awake or waking up and tossing and turning from my legs being so restless, and my ears constantly ringing all night. I wonder if those herbs were amazing and helping me through this or they were hindering the hormone therapy. I wish we had a way to find out. I really don't like feeling this way and the lack of sleep just effects everything else in my life and I just feel like I am complaining about my aches and pains all the time. I don't have another appointment with Onc for 12 months now, BC surgeon in 4 months. So my question is...does it get better? I am 3 months into a 7 year course. I am doing light exercise with light weights 4-5 times a week, eating pretty healthy, but I seriously feel like I can't stand, sit, lay, squat down, get back up...anything with it hurting like I have done a 3 hour intense workout and over done it and all I can think right now is that 7 years is a long long time!!! Any advice or feedback will be greatly appreciated, be it good or not so good :) Thanks for listening Sam
New member
Hi. I was diagnosed with mbc in 2021. An MRI done of my hip (me thinking I needed a hip replacement) revealed a bone lesion and further scans showed I had lesions in my skull, breast bone and right shoulder blade. Radiation helped with the pain in my hip and I am now able to walk unaided. I have been on letrozole and Verzenio (abemaciclib) since mid 2021 and so far results have been positive. Lesions have either shrunk or stabilised and there is no sign of cancer in organs. I know that one day treatment may cease to work but in the meantime I remain positive and enjoy every single day. I love to travel, cook and spend time with family and friends. I’m forever grateful for Bcna, my medical team and all the research that goes in to treatments for this disease. I know others are not as lucky as me and I wish everyone well on their individual journeys.Newly Diagnosed - Letrozole
Moderator moved @krisol comment to new discussion post in Newly Diagnosed: krisol NSW Member Posts: 1 May 16 Hi everyone, I’m new here. im started letrozole 1 month ago and I have middle joint pain specially in the mornings. I found that exercises help me a lot and I hope long term does not affects my bones. I hope will improve with the days until my body accept this medicine. Blessings for every one.
Hormone blockers
I have just completed radiotherapy and will start Letrozole in a few weeks. I am petrified having read the side effects experienced. I am in menopause and wonder if the impact will be less or if there are many who don’t have any side effects? Anyone with positive stories about Letrozole?
