DCIS, single mastectomy, no hormonal blocking therapy
Hello , Please I am looking for information/comments/ personal experience of receiving no hormonal bocking therapy post single mastectomy. Ive had a single mastectomy for a high grade DCIS , two areas, 5 weeks ago. Im reading so much information about hormonal blocking agents . Im 59 years of age and ceased my HRT immediately when I received my diagnosis. (recommended by my GP and Surgeon) I have been informed that I do not need any hormonal blocking medication. Are the hormonal blocking agents effective ? Are they only used when radiation has also been implemented? Im a bit confused . Many thanks.
Tamoxifen - any good news stories?
Hi all, I'm 54yo, just had a single mastectomy and my prognosis is looking good. Oncologist is just waiting for the Endopredict to return a result but is hedging towards Tamoxifen or similar. The more I read the more I'm stressing about taking any of these drugs (my mum was on it 40 years ago and from memory, it wasn't pretty). Are there any good news stories out there? or is it terrible for everyone? Thanks P
Hormone Blockers Weight gain & GLP-1s
Hi Everyone, I am 53 yeards old and 3 years into hormone blockers and am managing (barely) all the side-effects except for one. Weight gain. I have always been fit and active and I am working out more than ever and eating incredibly healthy and nothing seems to make a difference. I have slowly increased from a size 10 to almost a 14 since commencing hormone blockers. I have seen some medical evidence that GLP-1's at a low dose have been helpful for not just weight loss but also a reduction in other side effects as well. Has anyone else had a conversation with their oncologist regarding using GLP-1's and potential benefits? I don't like the thought of taking yet another drug but I am getting to the point of worrying about everything I eat and also cannot afford to keep buying another size up! If anyone has any info on this topic or knows of any specialists in this space I would appreciate it very much, Thanks!!
Giredestrant - SERD
Hello there, Reading the news coming out of the San Ontonio Breast Cancer Symposium this year (happening right now) and there is a very positive, yet early, study on a new SERD on Early stage BC in the Lidera trial. Does anyone know about this or is part of the trial? It seems that there was recruitment in Victoria? Keen to hear.
Taking collagen powder while on Tamoxifen
Wondering if anyone can help point me in the right direction? I am wanting to take a collagen powder supplement while taking Tamoxifen. I asked my oncologist and he suggested I check drug to drug interactions online but I am struggling to get a straight answer. Next time I see the pharmacist I will ask them but wanted to know if anyone has personal experience. Thank you
Early breast cancer treatment decision
Hi everyone, I’d really appreciate hearing from others in a similar situation. I’m young, not (as) close to menopause, and recently had a lumpectomy for a 12 mm, grade 1, ER+/PR+ HER2- IDC. Margins were clear, and there was no lymph node involvement. My Ki-67 is low (10%), and I’ve been told I don’t need chemo. The surgeon noted there was no calcification and no need for PET-CT. No problematic genes. My doctor recommended both radiation and tamoxifen, but I’m feeling unsure. Looking at tools like Breast Predict for hormone therapy, the benefit to mortality risk is minimal (0.3% for 5 years, 0.7% for 10 yrs, 1.1% for 15yrs). I'm very healthy, exercise daily for years, healthy diet, don't drink or smoke. My breast are above average and their tissue is very dense. Women in my family have had rough menopause - incl. severe heart issues so I'm worried about the tamoxifen side effects, and I'm thinking an MRI (?) every 6 months is enough. Given how small and slow-growing the tumour was, and how low my recurrence risk seems to be, I’m struggling with whether I really need both/ either radiation and tamoxifen. I know they each reduce recurrence in different ways, but I’d love to hear from others who had similar pathology — especially other younger/pre-menopausal women - If you only did one (or neither), how did you make that decision? I'm meeting with the medical oncologist for the first time this Friday and keen to have an intelligent discussion that may challenge the conventional/ standard treatment. if you have any research to share - that would be wonderful! I'm grateful for any insights or personal stories you’re open to sharing — I’m feeling a bit stuck and trying to weigh peace of mind vs. quality of life. Thanks so much!
Zoladex
Hi, so I’ve just been started on zoladex and I’m wondering about side effects. I feel like I suddenly have IBS or something. I’m going to the toilet 5-6 times a day. Everything I eat is giving me stomach cramping, almost like continuous period pains. I also feel nauseous a lot. Is this normal? Has anyone else experienced this? Does it calm down after a while? I’m scared to start taking the letrezol as well now in case it all gets worse. I was sent home from work today, first day back, because I was doubled over in pain from the cramping. It’s ruining my life and it’s only been 2 weeks.
Nausea after 3 days on Exemestane?
I tried Exemestane for 3 days and felt really nauseaous and stopped taking it. Nausea went away next day. Has anyone else had this side effect after such a short time? I found one old post on Reddit saying the same thing. My oncologist questioned that I could get such an extreme reaction after such a short time.
