Palbociclib-anti cancer drug effects
Hi Ladies Just wondering if anyone is on both Letrozole and Palbociclib, I am about to start the Palbo and hope I can tolerate it so I can go back to work. I am 61 and have stage 2 inoperable cancer at the moment and the oncologist wants to try and shrink it over the next 6 months. I am worried about the nausea and fatiique and as I work in primary schools walking and talking a lot, feel stressed just thinking about it, but really need the income to fund all these private treatments and meds.
Neuropathy- need some moral support
Hi all, I had one dose taxol and 2 doses herceptin. They have since put treatment on hold 3 weeks ago due to neuropathy in feet and legs (I was borderline for needing it anyway). Im now in a vicious cycle or spiralling anxiety and worsening symptoms, despite them only being mild to begin with. I’ve upped my antidepressants which will hopefully kick in soon. But I’m so scared that this is going to be permanent. I get zapping, tingling and varying numbness. Some days are good, where I barely notice, and other days, like today, it feels debilitating. I guess I’m looking for some good news stories or tips on what worked physically or mentally to help get you through this. many thanks, Anna
Post chemo / zoladex & letrazole side effects (hoping for some hope - please!)
Hello ladies, I finished 6 months of chemo (doxy then paclitaxcel) recently and then started on zoladex and letrazole last week. I am feeling VERY anxious all the time, very tired and flat - not like "myself" at all and really pretty non-functional. I can barely make a cup of tea and seem to just stare at walls when I'm home alone (often). I managed surgery and 6 months of chemo basically alone and unsupported and I coped. Now that I'm closer to family I seem to have really mentally crashed. Motivation is zero and the smallest things are an effort. I was more functional than this DURING chemo... Is this normal post chemo? A crash? Or is it the new hormone suppressants? Will it pass? Can anyone PLEASE offer me any words of wisdom or hope around recovering from chemo and the adjustment times to the hormone suppressants? Wishing you all so well. SDM.
Pathology results
Hey everyone, I’m trying to understand my histopathology report from my biopsy and I’m hoping someone here has answers, as I won’t get to see a doctor till the 19th November. This is what the report says: ”The cores of breast tissue are infiltrated by an invasive ductal carcinoma. The tumour forms solid nests and cords of atypical ductal epithelial cells displaying a moderate degree of nuclear pleomorphism. In addition, several multinucleated giant cells are noted indicating invasive ductal carcinoma with osteoclastic giant cells.” I also have a Ki-67 of 30-40%. My report also states the cancer is oestrogen and progesterone receptor positive and HER-2 low. I do have a good understanding of anatomy and anatomical terms as I’m a science teacher- and epithelial means skin cells and osteoclastic should have something to do with bones. So does this mean I likely have metastatic disease with Mets in skin and bone? I’m likely just having anxiety but because I have so long to wait for the appointment and I can’t call the line until Monday I’m hoping someone else has had similar results.Feeling "blue" on tamoxifen
Hello there, has anyone else felt flat, down in the dumps after starting tamoxifen? I have been on the little white pill 20mg for 2 months now, and my anxiety levels are also quite high, but I do have upcoming scans and alot of worries still. Any pearls of wisdom for helping to overcome my flatness? I exercise daily, trying to eat as healthy as I can. In all honesty I do miss a little bit of alcohol to help me relax!! Thanks ladiesMemory
For some as a result of diagnosis and treatment the effect on our memory can be distressing - fatigue or chemo induced or anything else in between, stress, anxiety, menopause! I have a sister who has early onset Dementia and on the road to diagnosis she was seen by a health professional, Neuro Psychologist. She has written a book and there's a precis of it here that some may find interesting or useful to someone you know Memory-wise - Dr Anne Unkenstein -- Allen & Unwin - 9781760296384 - Allen & Unwin - Australia (allenandunwin.com) Best wishes to all
another delay, sad and mad and very disappointed
Hi, I've had a disappointing week and I thought I would drop in with all you wonderful people and unload (sorry it feels like going down not up lately) I'm about 4 weeks into my 2nd time round, I had the lumpectomy in 2020 and now I'm ready for double mastectomy and not considering reconstruction. Had surgery booked for Friday 1st and I had a recent UTI but Thursday afternoon had the details and what was required then an hour later it was cancelled , I was so broken about that for a couple of days and just started to settle and now I am covid positive. When the test showed positive I just shut down don't really feel anything. I'm lost at the moment wondering what's next.. thank you all for being here, for your time and thoughts!!
No response to paclitaxel - anyone else?
Hi all, I was dx with early BC in August this year. I turned 40 this year. It's a grade 2(ish) invasive ductal. Hormone +ive, HER2 -ive. Because it was in my lymph nodes, my treating team wanted me to do chemo first (4x AC dose-dense, 12x weekly paclitaxel). I'm on the 4th pacli cycle (it's infusing as I type!) I had a progress ultrasound last week and when I spoke to my onc yesterday, he was a tad concerned that the tumour doesn't seem to be responding to this drug. He talked about maybe stopping this drug and going straight for surgery and hormone therapy. The chemo nurses assure me that people change treatment regimens all the time, and I tell myself that monitoring and reassessing is a GOOD thing. But I'm still in a dither. Also, every twinge, niggle, and sensation anywhere near ol’ leftie has me jumping out of my skin in panic, convinced that the end is nigh. So my questions to you all: Has anyone else been in the same situation? On a scale of 1 - 10, where 10 is Beet-faced-embarassed, how silly am I going to feel about this anxiety in a week or so? Is there anything I should do to get prepared for maybe having surgery(?) in the next few weeks? I had totally bumped that down the road as a problem for 2022! TIA!
