Forum Discussion

Renee44's avatar
Renee44
Member
12 years ago

Confused er- pr+ her2-

Hi everyone, Well I've seen my pathology report now and I'm confused. Contrary to my original core biopsy and what I thought the surgeon said - the report has me as stage 1 (must say I'm glad with that), grade 3 - now this is where I get confused! I'm er- pr+ (weak) and her2-, also notes Ki-67 (95% cells positive). Note my original core biopsy was pr- er-. Is anyone else in the same boat - in a nutshell what does it mean?

3 Replies

  • Thanks Annie. Surgeon has indicated it is highly unlikely that I'm suitable for hormone blockers but that my oncologist will advise further. My appointment with the oncologist is early July so hoping to be better informed then. I've got referrals for ct and bone scans so getting those done before my appointment.
  • Hi Renee,

    This is Annie from BCNA. I can understand that pathology results can be really difficult to understand. If you have another consultation with your surgeon or medical oncologist soon, they're very well places to answer any questions that you may have. Don't be afraid to ask them to explain things a few different times until you understand - remember, they are there to help you.

    In the meantime, I thought I'd point you towards BCNA's pathology fact sheet which may also help to clarify things. You're welcome to order a copy by visiting our online shop. You may also find it useful to take it along to your next medical appointment.

    All the best

    ~Annie

  • Hi

     

    I am ER+ PR+ (90%) and HER2 -, I had clear margins in the surgery, and no cancer in the lymph nodes. Pathology rated tumor as Grade 2.  these were all great results. except when I saw the oncologist - I had a high Ki67 which to her meant my tumour was aggressive (it means it was a "Proliferative" tumor according to my oncologist) and acting as an aggressive tumour. So she recommended that I have chemo, which I had my last dose last week. It is about prevention. 

    I think you do need to wait for surgery pathology as they will test the whole tumour, not just a small part of it. 

    not sure if that helps you, you should be guided by your team. but thats my story. 

     

    Marg xx