Forum Discussion
The Joys of Dexamethasone
Well, the side effects of Dex have truly hit me in the last few days! Less than a week out from my third chemo and I am sick of feeling like a bloated lump who gets home each night with cankles and s...
This was in 2004
http://www.uchospitals.edu/news/2004/20040315-chemo.html
Fast forward 2015
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839331/
And maybe Dex has a lot to answer for. It certainly does strange things to our body.
There is now good evidence that at least part of the chemo effect is off target ( not related to DNA ) - specifically chemo can cause stimulation of innate and adaptive immunity - and part of that ties in with blood sugar levels, insulin levels, IGF...
Dex modulates all that. I feel it is worth asking oncologists how much do we really need to take and what is the dosage optimal timing as it relates to individual chemo protocols.
I take some Dex with my chemo - I was allowed to take if needed for nausea with AC, and I just managed on ondansetron - they are strict on the pre dose with Taxol because of the concerns over allergic reactions.
http://www.uchospitals.edu/news/2004/20040315-chemo.html
Fast forward 2015
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839331/
And maybe Dex has a lot to answer for. It certainly does strange things to our body.
There is now good evidence that at least part of the chemo effect is off target ( not related to DNA ) - specifically chemo can cause stimulation of innate and adaptive immunity - and part of that ties in with blood sugar levels, insulin levels, IGF...
Dex modulates all that. I feel it is worth asking oncologists how much do we really need to take and what is the dosage optimal timing as it relates to individual chemo protocols.
I take some Dex with my chemo - I was allowed to take if needed for nausea with AC, and I just managed on ondansetron - they are strict on the pre dose with Taxol because of the concerns over allergic reactions.