Hi ladies, just a note re Tamoxifen. I had so many issues taking this drug such as nausea that progressed into vomiting at night and depression that left me in crying all day in bed, that I ended up in tears at my oncologist's office twice. Eventually, he took me off it and sent me for some tests. Within 7 months of taking it, my liver was showing disease where before it was perfectly normal! If you are feeling low or have recurring vomiting issues, please talk to your Dr about it as soon as possible. Not all the possible side effects diminish in time, sometimes they are a warning of deeper issues with the drug. There are a few different alternatives out there that may be more suited to you, don't be afraid to try them.