Hi ladies, sorry for the late reply, rash hasn't got any worse but the temp seems to have gone today. I am on antiobiotics for a sinus infection but Dr was quite sure that that wasn't the cause, she said she has seen women have a delayed reaction to tamoxifen so wants me to see the Oncologist asap. I am going to back to my normal GP on Monday if no better. I am taking an anti-histamine and panadol and seems to keep the itch at bay but the hot flushes makes my skin feel like its crawling. Thanks for the advice :)