I've had on-going pain and stiffness for five years, probably the anti-oestrogen meds and I've tried about ten different drugs, none made any difference. I had a very bad reaction to Lyrica, made me quite high which I hate and I had what I called mental black outs. Not memory loss but actually not knowing or remembering why and how I was getting out of the car at the local shopping centre. Very scary. I only took them for a few days and then phoned the chemist to find out if I could stop taking them, he gave the ok. We are all unique and what works like a charm for one causes untold problems for another. Please let us know you get on.