I didn't want to start a new discussion so thought I would use someone else'. I have heartburn issues since the commencement of chemo. I finished all treatment over a year ago and slowly took myself off the heartburn tablets over six months. However I have since had heartburn and ongoing back issues and put myself back on to the heartburn tablets. Back problems have eased considerably as that tightness is no longer around my torso. Three days after resuming the omeprozale, I started having depression attacks out of the blue much like I had during treatment. I decided to see if there was a link. Yep, not common, but heartburn tablets can cause depression. So, pain or depression? Neither option sounds appealing.