I have done theTamoxifen and Arimidex thing and neither drug was tolerable. I have a friend who is on Aromasin and its side effects are making her life a misery. The choice to take these treatments lie with each person and in terms of prearation for Arimidex would be to ensure the systems that can react to it are as healthy as they can be. Reducing processed food intake and switching to Fresh vegeies ++ and Yoghurts to increase your Calcium, reduce your fluoride intake if you can as it displaces Calcium and can cause brittle bones. Any sort of pain is tolerated to a wide variety degrees. Bone pain can come from inflammation and an anti-oxident can reduce that. A non genetically modified flax seed in liquid or capsule form can assist and it benefits combating the effects of stress. Yhe biggest factor is mental resistence. We have minds that can increase or decrease our perception of problems. The reason Doctors often do not mention all the potential side effects is because some people can psychenically develop a lot of mentioned symptoms. My years as a Nurse saw that happen many times. I believe if you follow a Mantra of Mind over Matter your health, your immune system and pain management beomes much easier to increase its efficiency. Simply put; if you don't mind then it doen't matter! Boom Boom! Smile and remember Cancer doesn't kill you, it makes you stronger! Mieke/Joanna