I’m on tamoxifen and did respond to the Melbourne trial, but had to wait a couple of months due to other commitments before meeting up with the researcher. I tracked my hot flushes prior to responding, and I was hitting the study required level of 50+ moderate / severe a week.
However, between signing up and meeting the researcher, I was in a hot climate for 3 weeks and had panic-inducing swelling in the breast. I couldn’t walk because of the heat, so I swam every day bar one for three weeks.
I kept it up when I got home, as it certainly helped (the swelling is completely gone now although sometimes I still feel a bit funny there, so keeping on with exercise and medical fabric mobiderm for edema). However, when I went in to meet the researcher and I did the test run of tracking my hot flushes, I only had 37 per week of moderate / severe.
I hadn’t realised it, but the exercise seems to be helping my hot flushes. It isn’t a cure though - I’ve been doing a ridiculous amount of exercise in order to improve my body’s ability to regulate blood pressure so it doesn’t go low (that’s working fine!) and I still do get hot flushes, just not as many and not as severe.
I hope that they can get good results from the trial - fingers crossed.