Forum Discussion

Smellycrackle's avatar
7 years ago

Femara and post menopause

I have been on Letrozole also known as Femara since last April.  This only work if you are post menopausal only (from what I have read).  My cycles finished after my 2nd Chemo - so back in December 2016, and they have not returned.  I have had a hormonal blood test and my results come back as NOT post menopausal. I am concerned that this isn't doing anything because I am not post menopausal.  Concerned!!!  Anyone else not post menopausal but on this too?

17 Replies

  • I took Tamoxifen for five years. It didn't work. The goal posts keep moving when it comes to cancer treatment. That is probably a good thing.
  • My understanding is an AI is considered a more effective drug as it more thoroughly prevents the amount of estrogen being produced. But don't quote me, I'm not a doctor. My oncologist said I was 50/50 between an AI and Tamoxifen. I said I wanted the one that gave me the best chance to live until I'm 80. She said she favoured the AI by a fraction.
  • I am going to go and see my GP tomorrow.  The oncologist said if your period returns have the blood test that checks your hormones.  I haven't had my period return but wanted to see what my hormone levels were.  Today they tell me they are in the range that is Not post menopausal.  I want to be taking tablets that are helping keep this at bay - not something that is doing nothing at all - except give me stiff joints...
    Although kmakm - you too have been prescribed Letrozole - so maybe there is a method in their madness.

    Hopefully the GP can help me out tomorrow..   Ill mention Zoladex.  But I wonder why dont they put us on Tamoxifen if we are not post menopausal.....   
  • If your GP did the test you need to either have some robust discussions with them now about how, and when, aromatase inhibitors work and what happens next, or get back to your oncologist now.
    I don't know where you live, but the reality is that GP care is pretty much it for many of us. If yours requested the test, its likely they are a bit switched on and if you trust them push them to either refer you up the libe or do something about it. AIs are pointless if your hormone status is wrong.
  • Send him an email saying you are wondering. He won't want you to worry. You could also ask your breast care nurse.

    I'm about to start Letrozole and as it was breast cancer stress and treatment that stopped my periods only last December, my oncologist is going to blood test me every three months. If the LSH & FSH hormone levels go up (released by the brain to try to get the ovaries going again) she'll give me a Zoladex injection once a month.

    Let us know how you get on. Best of luck. K xox
  • No, there has been no mention of Zoldex..  I am thinking as my periods have stopped and have not returned they "the oncologist" puts me in the post menopausal category.  Dont get to see him again until August tho to bring this up again..

  • Are you having Zoldex injections? That's the usual thing if you are not menopausal--it disables ( for want of a better word) you hormone production. Mxx