Depends a lot on what your side effects are! Losing my hair wasn't noticeable to most people - I wore a wig, most people didn't know my hair had gone and as I wear glasses, my eyebrows and eyelashes aren't so visible. They lasted reasonably well and eyeliner and eyebrow pencil worked well for the rest of the time. I didn't have nausea or fatigue - both of which must be really hard to deal with. I looked really well so while I made no secret of treatment, workmates and most people treated me normally because that's what they saw. I was lucky enough to maintain a normal life, so apart from some occasional "fed up with the whole thing" moments, I got through chemo. My major side effects were later, I have an arrhythmia (which is easy to manage), lymphoedema (ditto) and my feet have never really recovered from peripheral neuropathy. Apart from taking some pills, wearing a compression sleeve (which you can learn to hate or learn to get used to), my only long term side effect is giving up heels! For which, having worn them for five decades, mostly the higher the better, my hamstrings and knees are eternally grateful!