I agree @primek, we are all different and some of us bring other health issues to the table with us too. Aside from BC I also live with scleroderma (CREST type), I had been having so called "silent reflux" and only when a camera was threaded down to my vocal cords, was the reason for my four months long "laringitis" found...I actually had ulcers lining my entire esophagus as well as my vocal chords in my larynx. I still take medication for this now. My record during AC chemo for constipation was 15 days....count them...15... I had been trying to resolve this matter from day four without success. When I eventually hit the jackpot, I ended up with a rectal tear. When on Paclitaxol, I spray painted my loo a total of 12 times in one day. I couldn't even fart for the entire three months of taxol, except on the loo, in case I got more than I bargained for. Needless to say I took medication for both these extremes of bowel malfunction. As regards pain, I experienced very little following my bilateral mastectomy with node clearance, even after a massive bleed resulted in me being rushed back to theatre as an emergence and opened up. The bleeders were clamped off. That was eleven units of blood and four of plasma...a doozy of a bleed and also returned from the second visit to theatre with two broken ribs. (I also have severe osteoporosis). I do now, however take one pain tablet before I go to bed after having brain surgery a few weeks ago. I had my right internal carotid artery aneurysm clamped which resulted in air and blood around the brain. This is still resolving. I feel no guilt about this @"Patti J" " and will continue to do so (under my neurosurgeons care) for as long as I need to.