Hi Celeste,
Tamoxifen is given to both pre and post menopause women with eostrogen receptive cancers.It's probably not tolerated as well when you are pre meno.from what I am told.It is supposed to block eostrogen from breast tissue.The other drugs you mentioned(aromatase inhibitors)can only be used by post meno. women.When your ovaries stop making eostrogen your adrenal gland takes over after meno.to produce some eostrogen.These inhibitor drugs(Arimidex etc.)stop the adrenal gland from doing that.Adrenal gland sits just above the kidney. That's my very simple take on it!! My doctor has prescribed me a very small dose of an antidepressant called Endep.(10mg).It sometimes helps with hot flushes ,sleepless nights,aches and pains and feeling down.I think it has helped a little.It certainly helps with sleep and mood anyway.It's sometimes hard to get moving in the morning though and then I need a coffee -what a chain reaction!
I've tried the other drugs 7 years ago when the Tamoxefin didn't agree with me and they were just as bad.So I am committed to making the Tamoxifen work this time and so far so good.(well sort of).
Tonya