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Hi @Jenni22 thanks for sharing this thread, the question “Is it worth it?” seems like one many of us ponder quietly. This thread and the generous responses are very helpful for anyone (like me) still coming to terms with the unexpected interruption and impact that a breast cancer diagnosis can have and the reality that this can extend beyond ‘active treatment’ phase. It has reminded me what a gift it is to have treatment and recurrence prevention choices and I am so grateful to everyone - like you - for participating in trials, research and clinical treatment. By voicing your experience I believe it really advances the research and hopefully improves quality of life for everyone taking these medications and living with cancer or a risk of cancer recurrence. A big thank you.