Hi @elisewjk, I’ve had skull and spine mets since my initial diagnosis March 2018, which I had been taking Ribo/Letro combo for since June 2018. But when third skull met came up August 2020, my Oncologist changed me over to Tamoxifen. The effects are similar ie it makes me feel menopausal - run hot and cold. Less tired....I think...who knows really. And initially it made me feel like I was coming down with the flu - but that seems to have eased. I hope the effects are minimal for you and that it works. Have a good weekend. Hugs back. :)
