goodbye xeloda hullo to navelbine

I noticed a few comments from those starting abemaciclib, and was wondering if the side effects have improved.   I have started on Letrizole and Vereeniging/Abemaciclib and ams struggling with the side effects.  I am in the fortunate position in that both these drugs are being given as a preventative measure.  I don’t have Mets, but am at very high risk of re-occurrence.  Originally diagnosed with bi-lateral early breast cancer, one was triple negative, the larger more aggressive (grade 3) was estrogen positive.  Hade 6months chemo, plus radiotherapy and double breast reduction.  The abemaciclibb is part of a trial that is showing reduction in recurrence rates of around 6%.  I’ve only been on these for 5 weeks, and side effects are manageable, but I am struggling with diarrhoea, fatigue, vertigo and just generally feeling unwell.  I was so looking forward to end of my treatment and getting some energy back, but now with two years ahead of me on this regime, I am wondering if it is worth it.  Keen to hear if anyone else is in a similar position and how you are managing the pros and cons of the treatment options and quality of life.

Thanks
Jenni