Palbociclib trial ladies(how you doing)
Just wondering how you other ladies on this drug are faring. I'm on the maximum dose and seem to be doing quite well. I'm on cycle4 and have had were side effects. Hopefully you are all going well.
Forum Discussion
Hi Ladies, how are you all progressing?
I have been very quiet of late, trying to simpify my life but for some reason I seem to be busier than before???
I am onto the 7th cycle of Palbo. I have been dropped to 100mg due to recurrent low neutrophils. I wasn't surprised, I had the same issue on Chemo and was on Neulasta for the whole treatment.
I am now on 3 monthly reviews and have sorted out the side effects to some degree.
The hot flushes have eased in severity with the cooler weather. HALLELUYAH!
BUT the joint stiffness and pain have increased markedly. SIGH.
I wasn't really having much problem with that in the beginning, just a surge of it in my knees in the first three cycles and then it eased to be barely noticeable.
My hands and wrists are also suffering.
I started having finger pain and tingling at the end of cycle 5.
Not all the time and it rotated around my fingers each day. It eased off in the week off, but is creeping back again now I am back on the Palbo, week 2.
I have reported it and will monitor it. I can live with it as it is mild if it eases off each break, but otherwise I think that would be a reason I quit if it increases.
A lot of the hot flushes and awful nausea I have identified are very much linked to stress.
Even the mildest stress sets them off. I guess it helps to know, not that I can do much about it, though.
And coffee also brings them on. I am going to have to tough that one out, I am not giving up my coffee, it is the one thing that makes getting out of bed appealing.
I am sorry to see on the news that Palbo hasn't been put on the PBS due to lack of agreement on cost but so good to see that the other one has got approval. I was a little alarmed to see that the Palbo is $5,000 a month, it did make me value it a little more.
I am currently going to TaiChi, Music Therapy and Exercise with the Physiotherapists at Wyong Hospital, all through the Central Coast CanCare program. I am determined to lose a lot of weight for my reconstruction surgery at the end of the year.
Today I managed to jog on the mini trampoline, I haven't jogged in years!
I had my first mammogram, 3D tomography and ultrasound following my diagnosis.
All clear.
I have fatty lumps down my mid sternum area and quite a bit of pain to touch there, which the Onc thinks may be either arthritis in my bones from the Letrazole or possibly a side effect of the Palbo, it is listed as one of the side effects. As long as it isn't something serious, I can live with it.
I hope everyone else is having minimal side effects too
I have been very quiet of late, trying to simpify my life but for some reason I seem to be busier than before???
I am onto the 7th cycle of Palbo. I have been dropped to 100mg due to recurrent low neutrophils. I wasn't surprised, I had the same issue on Chemo and was on Neulasta for the whole treatment.
I am now on 3 monthly reviews and have sorted out the side effects to some degree.
The hot flushes have eased in severity with the cooler weather. HALLELUYAH!
BUT the joint stiffness and pain have increased markedly. SIGH.
I wasn't really having much problem with that in the beginning, just a surge of it in my knees in the first three cycles and then it eased to be barely noticeable.
My hands and wrists are also suffering.
I started having finger pain and tingling at the end of cycle 5.
Not all the time and it rotated around my fingers each day. It eased off in the week off, but is creeping back again now I am back on the Palbo, week 2.
I have reported it and will monitor it. I can live with it as it is mild if it eases off each break, but otherwise I think that would be a reason I quit if it increases.
A lot of the hot flushes and awful nausea I have identified are very much linked to stress.
Even the mildest stress sets them off. I guess it helps to know, not that I can do much about it, though.
And coffee also brings them on. I am going to have to tough that one out, I am not giving up my coffee, it is the one thing that makes getting out of bed appealing.
I am sorry to see on the news that Palbo hasn't been put on the PBS due to lack of agreement on cost but so good to see that the other one has got approval. I was a little alarmed to see that the Palbo is $5,000 a month, it did make me value it a little more.
I am currently going to TaiChi, Music Therapy and Exercise with the Physiotherapists at Wyong Hospital, all through the Central Coast CanCare program. I am determined to lose a lot of weight for my reconstruction surgery at the end of the year.
Today I managed to jog on the mini trampoline, I haven't jogged in years!
I had my first mammogram, 3D tomography and ultrasound following my diagnosis.
All clear.
I have fatty lumps down my mid sternum area and quite a bit of pain to touch there, which the Onc thinks may be either arthritis in my bones from the Letrazole or possibly a side effect of the Palbo, it is listed as one of the side effects. As long as it isn't something serious, I can live with it.
I hope everyone else is having minimal side effects too