Hello @Chris, I had Prolia injections - 9 in all - since 2013 with no side effects. My Hip T-score improved from -1.6 to 0.96, and spine T-score from -1.66 to 0.32, so it definitely improved my density by slowing down bone turnover. During this time I regularly used the treadmill @ 6 for 30 mins/day and used light handweights. A year ago I stopped, but my bone density has stayed the same since. I think like all our meds, the results are individual. The Bone Clinic is excellent but too far for me. All the best with your decision. Michelle x