Hi ladies. Sorry for the delay in replying to your helpful posts. The first two days were hell and I went back to my doctor she suggested taking anti nausea tablets before the letrozole for a few days and I am pleased to report they did the job. However I will get some ginger just in case it comes back when I stop the maxolon. The hot flushes have started I did not think that would happen quite so soon. I am well past menopause so was not looking forward to that aspect but not too bad so far. No aches and pains yet! I have been going to the gym for a while so hopefully that will help. Romla I will keep the krill oil in mind it is good to have some back up ideas and that it is ok to take while on letrozole. Anyway thanks again, time for bed for me. I hope you all have a great day tomorrow.