Usually the specific pain to aramatose inhibitors such as letrazole are in the fine bobes of hands, wrists, ankles and feet. Mimicking arthritis. I had all this initially but over 6 months improced and dramatically improved with exercise. If I'm still fir too long I'm stiff in ankles still and waddle a bit until I get moving again. Any artgritic joint you might have might be more affected...like my kbee and back but now exercising these give me very few issues. Hope the same for you.