Wow!! I'm so overwhelmed with the responses to my original questions around Anastrozole!! I had a great chat with my oncologist and decided to have a trial period off Anastrozole. I have been off it for 8 weeks now and I'm feeling so much better, I'd almost say I'm back to my old self. Still have a few aches and pains but in general nothing compared to how I was feeling. I have picked up my script for Tamoxifen but haven't started taking it yet..... a couple more days. I'm well aware Tamoxifen comes with its own side effects but hoping I won't be effected the way I was on Anastrozole. Thank you to everyone that took the time to post opinions and experiences, I'm truly grateful.