Try and stay on the drugs if possible. You are describing normal symptoms many women seem resigned to live with for 5 years. However, statistics (don't you love statistics) reveal at least 50% do not finish the 5 years. If the symptoms are too intolerable for you perhaps your Oncologist can try something else. I didn't need to have chemo - I chose it because it gave me another 4% survival chance. Had I decided not to have chemo I would never have seen an Oncologist and doubt I would ever have started the drugs in the first place as my GPs don't seem to have the same conviction as the Oncologists. After trying every single one of those drugs the last thing my Oncologist said to me as I walked out the door for the last time was "you could be dead in 18 months". Nice!