Thanks Janey. Yes, it certainly does turn your life on its head! I have a book from my surgeon that my husband has read and I haven't. He said it explains so much and has a good title anyway......Breast Cancer - Taking Control. So will stick my head in that today and it may explain some things on my histology report. Either way the poor oncologist is going to be hit with a long list of questions tomorrow! I too am on herceptin once radiation is finished I will be on tablets for five years too. I have read a lot of good things about herceptin and so glad that we have it. I have thought so many times how lucky I am to be in this day and age and have access to all these things. Maree x