Xeloda
I have TNBC, diagnosed Jan 2017, AC, Taxol, Lumpectomy, Carboplatin, Radiotherapy ( 25 +5). Finishing mid January 2018. I did a bit of research and asked about Xeloda post op and post radotherapy. Ju...
Forum Discussion
Hello Padley,
I am also (or was) TNBC and currently taking Xeloda (capecitabine) post neoadjuvant treatment and surgery to avoid recurrence.
Below is a copy of text I wrote on a previous forum post.
For me, after neoadjuvant treatment and recent surgery, I am now on a course of oral capecitabine (xeloda) to destroy any micro metastatic cells that might be lurking after the surgery, given I had positive nodes removed under my arm, (PCR in my breast and no other cancer elsewhere in my body). My understanding is capecitabine is an existing approved drug in Australia used for treatment of metastatic cancers. There is a recent study in Japan called CREATE-X which had exceptional results from giving capecitabine to people with positive nodes or not receiving PCR after neoadjuvant treatment to increase their disease free survival rates. The results from the study were extremely favorable to TNBC.
I am truly grateful to my surgeon and oncologist for being given capecitabine as my chances of recurrence after neoadjuvant treatment were much higher than I would have liked (or what the would have liked too). I suspect with the results from the Japanese study the use of the drug will increase for those with TNBC similar to myself.
I am now on my 4th cycle and have really had minimal issues, the main being some tiredness and dry skin. I've remained working as a teacher / librarian and recently returned from an overseas holiday while taking the drug.
In answer your question about why you are being offered capecitabine now and not previously, I think it is to do with a very recent change in treatment for TNBC after neoadjuvant treatment, not so much a change in your results. As I said previously, I am very happy to have this opportunity as I want to remain (and will) cancer free.
Have a wonderful trip to the UK.
Jen
I am also (or was) TNBC and currently taking Xeloda (capecitabine) post neoadjuvant treatment and surgery to avoid recurrence.
Below is a copy of text I wrote on a previous forum post.
---------------------------------------------------------------
For me, after neoadjuvant treatment and recent surgery, I am now on a course of oral capecitabine (xeloda) to destroy any micro metastatic cells that might be lurking after the surgery, given I had positive nodes removed under my arm, (PCR in my breast and no other cancer elsewhere in my body). My understanding is capecitabine is an existing approved drug in Australia used for treatment of metastatic cancers. There is a recent study in Japan called CREATE-X which had exceptional results from giving capecitabine to people with positive nodes or not receiving PCR after neoadjuvant treatment to increase their disease free survival rates. The results from the study were extremely favorable to TNBC.
I am truly grateful to my surgeon and oncologist for being given capecitabine as my chances of recurrence after neoadjuvant treatment were much higher than I would have liked (or what the would have liked too). I suspect with the results from the Japanese study the use of the drug will increase for those with TNBC similar to myself.
---------------------------------------------------------------
I am now on my 4th cycle and have really had minimal issues, the main being some tiredness and dry skin. I've remained working as a teacher / librarian and recently returned from an overseas holiday while taking the drug.
In answer your question about why you are being offered capecitabine now and not previously, I think it is to do with a very recent change in treatment for TNBC after neoadjuvant treatment, not so much a change in your results. As I said previously, I am very happy to have this opportunity as I want to remain (and will) cancer free.
Have a wonderful trip to the UK.
Jen