Forum Discussion
Understanding Ki67 index
Hello, I was diagnosed with breast cancer in October and had single mastectomy on 20/11. It came back as Stage 2A, HR+ HER- , grade 3, 2.7cm, no lymph node involvement, clear margins. Surgeon initiall...
Hi all,
newly diagnosed in November with HR+, HER2-, IDC, Stage 1b, grade 3, ki67 30%. This is my second diagnosis, with my first occurring in 2013 but it was TNBC. I’m also a BRCA2 mutant. I’ve had 2 surgeries to excise lump and try for clear margins. I have previously had a BMX with implant reconstruction. This cancer grew under the skin, in a tiny piece of breast material. I’ve been advised chemo is not necessary due to size of tumour (9mm), no node involvement, and I’m post menopausal (56yo). I’m taking anastrozole. Oncologist said chemo is ultimately up to me. If my tumour was 1-1.5cm then they’d advise chemo due to grade 3 & hi Ki67. I am finding it difficult to make a decision re chemo. I had TAC in 2013 and it was hell. It’ll mean time off work (I am single), and loss of income. My breast surgeon has also advised to have another mastectomy to remove my recon and as much skin as possible to reduce the risk of further recurrence. Recon in the future is not on the table. I’d love to hear from those who’ve had similar tumour size, grade etc and what treatment you had.
newly diagnosed in November with HR+, HER2-, IDC, Stage 1b, grade 3, ki67 30%. This is my second diagnosis, with my first occurring in 2013 but it was TNBC. I’m also a BRCA2 mutant. I’ve had 2 surgeries to excise lump and try for clear margins. I have previously had a BMX with implant reconstruction. This cancer grew under the skin, in a tiny piece of breast material. I’ve been advised chemo is not necessary due to size of tumour (9mm), no node involvement, and I’m post menopausal (56yo). I’m taking anastrozole. Oncologist said chemo is ultimately up to me. If my tumour was 1-1.5cm then they’d advise chemo due to grade 3 & hi Ki67. I am finding it difficult to make a decision re chemo. I had TAC in 2013 and it was hell. It’ll mean time off work (I am single), and loss of income. My breast surgeon has also advised to have another mastectomy to remove my recon and as much skin as possible to reduce the risk of further recurrence. Recon in the future is not on the table. I’d love to hear from those who’ve had similar tumour size, grade etc and what treatment you had.
Thanks 🙏🏻