How many treatments has she had @strongtogether ? I don't know much about carboplatin but with taxol, the suggested regimen (12) is what most people can stand not the minimum needed because they don't really know what the minimum is. Given this, they often stop it at 8 if the pn is getting concerning. Another option (again, I can only talk about taxol) is possibly to have an extra week in between to see if the pn settles down a bit. I think it's important to discuss it with the onc and find out the reasons and options.