I haven't heard of this for neulasta( I think that's the same), but interestingly I was put on loratadine after having hives during my first chemo (fec) and subsequently developing a rash a few days after this. My onc said it would be good to take loratadine for the duration of my chemo (6cycles) I was put on Neulasta for my second chemo after being found to be very neutropaenic after my first cycle. Therefore, when I have had Neulasta, I have always been on regular loratadine, and have only experienced very mild bone pain, not requiring pain relief. I hope it helps you, good luck!