I had the deep and meaningful with my oncologist at dose 10. My fingers weren't too bad but my feet were completely numb in places, extremely painful in other places and I was really worried about being able to walk if it got much worse. He wanted me to complete the course of 12, but wasn't too worried about the last one. Matter was resolved by finding a lump under my right arm (totally benign schwannoma) but that did rather focus my thinking differently! I finished the course, started taking vitamin B, my feet didn't get worse but have taken a long time to recover. The painful part recovered best, still have numb bits after 3 years but doesn't affect anything. Anything anyone suggests that will minimise the impact is worth doing (such as vitamin B). Still think it was worth doing the full treatment!! Good luck.