Hi @Gerryb, I've only had one round of AC, due to have my second round this Friday - I'm having 4 rounds of AC over 12 weeks then 12 weekly doses of paclitaxel. I found the first 5-6 days the worst. I had body aches and nausea within hours after having the chemo then it was mainly nausea and fatigue over the next 6 days. I got a sore mouth on and off but no real ulcers. I drank heaps of water for the first week or so - at least 2 litres a day - and I think this helps to flush the drugs out of your system and to help your poor kidneys and liver. I didn't really have an issue with constipation but I was drinking heaps of water and eating high fibre veges and nuts so this may have helped. I agree with @ccasper, if you can manage a walk each day, this may help the fatigue. About 7 days after the treatment, I actually felt pretty normal and have been feeling really energetic. I have a feeling as I go along with my treatment, I may not recover as quickly each time. Good luck for tomorrow and let us know how you get on xxx