I've done a lot of reading about this. Primarily because taking Tamoxifen was only going to improve my 10 year out come by less than 2% at best. Yet, given I've currently got long term sleep and joint issues the chances of me lasting long on Tamoxifen was low. So, what I do know is my vitamin D levels have been low for years. Plus, I'm off to my GP in a few weeks to get bloods done on exactly how out of wack my estrogen levels are, as well as what is happening with Vitamin D, and whatever else. I want to get them better than 'normal'. I want to get them at optimal. I've also started adding flaxseed to my breakfast. Whilst I'm trim, my fitness isn't great. So, I'm going to work on improving that too. Good luck everyone with whatever journey you choose. xx
Vitamin D may increase survival for
breast cancer patients
https://www.medicalnewstoday.com/articles/314017.php
Published
Thursday 10 November 2016
High vitamin D levels have been associated with higher
survival rates.
Some studies have suggested that the active metabolite
of vitamin D - known as calcitriol - may be anticancerous. Administering
calcitriol in mice has been shown to stop the proliferation and growth of
cancer cells, reduce tumor blood vessel formation, and stimulate cell death.
Although there are not yet enough clinical trials in
humans to prove this, some clinical and preclinical studies indicate that
avoiding vitamin D deficiency and taking vitamin D supplements might be a
cost-effective and safe way to prevent cancer and improve prognosis in patients
already diagnosed with the illness.
"Our findings provide compelling observational
evidence for inverse associations between vitamin D levels and risk of breast
cancer progression and death," the authors conclude.
A feasibility study revealed that 84.4 percent of
recently diagnosed breast cancer patients had already started taking vitamin D
supplements.
Association between Vitamin D
deficiency and Breast Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510119/
2017
May-June
Findings of this study show that vitamin D deficiency
is associated with risk of breast cancer.
Treating
Cancer Naturally: 11 Strategies That Work
https://thetruthaboutcancer.com/treating-cancer-naturally/
2016
#5.
Vitamin D
Because vitamin D is a fat-soluble nutrient, it is
important to take the supplement with a fatty based meal for optimal absorption
One of the key functions of vitamin D is its ability to
balance inflammatory pathways linked to cancer and promote the production of
proteins such as GcMAF which regulate cancer cells.
GcMAF requires vitamin D in order to be created and
fulfill its vital functions to maintaining the health of all cells and tissues.
GcMAF has been shown to reverse breast cancer by preventing cancer cells from
multiplying.
The Effect of Flaxseed in Breast
Cancer: A Literature Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808339/
7
February 2018
Some studies have shown that the intake of omega-3
fatty acids is related to the reduction of breast cancer risk. In animal
studies, α-linolenic acids have been shown to be able to suppress growth, size,
and proliferation of cancer cells and also to promote breast cancer cell death.
It also works as an antiestrogenic because its
structure is very similar to the main form of estrogen, which allows its
binding to the cell’s receptors, thus inhibiting the growth of cancer cells.
Observational studies
indicate that flaxseed consumption (approximately 32 g/daily) can reduce breast
cancer risk.
Ingestion of flaxseed or
bread containing this ingredient is associated with a 20% reduction in the risk
of breast cancer, in accordance with the protective effect observed in lignans
from other vegetables.
Both the monthly and
weekly/daily consumption of flaxseed (approximately 32.5 g) and flax bread (1
unit, roughly 2.5 − 5 g of flaxseed) were associated with a significant
reduction from 18 to 24% in the risk of breast cancer in all women. It was also
showed that flaxseed only reduced breast cancer risk in postmenopausal women,
while flax bread reduced breast cancer risk in both postmenopausal and premenopausal
women (52).
In another clinical trial,
researchers selected about 45 premenopausal women with a high risk of
developing breast cancer (either with suspicious breast biopsies or former
breast cancer survivors) and they gave them 50 mg of SDG lignan daily, or the
equivalent of two spoons of powdered flaxseed. The researchers conducted needle
biopsies on the breast tissue, both before and after the study, which lasted a
year. Results showed that, on average, women had less breast precancerous changes
after a 1 year period of taking daily flaxseed lignans, than they had before
they started being studied and also that 80% (36 out of 45) had a decrease in
the Ki-67 levels––a biomarker that signals the increase of cell proliferation.
According to this clinical trial, SDG lignan can reduce the risk of breast
cancer.
Breast Cancer; Making the Case for
Lignan Flaxseed Oil
https://bionatures.com/blogs/news/18674607-breast-cancer-making-the-case-for-lignan-flaxseed-oil
We suggest that every woman take at least one tablespoon
of lignan-rich flaxseed oil daily to reduce her risk of breast cancer and
minimize the potential for it to spread, should it occur.
Lignan-rich flaxseed oil is unique. Unlike regular
flaxseed oil, the lignan-rich flax particulate from flaxseeds is retained in
the oil, delivering powerful cancer fighting lignan precursors.
Once consumed, lignans found in flaxseed are converted
to mammalian lignans. These mammalian lignans bind with estrogen receptors,
where studies suggest they may induce the production of a special sex hormone
binding compound. This compound, known as sex hormone binding globulin (SHBG),
regulates estrogen levels by removing excess estrogen from the body. Lignans
are thought to be estrogen modulators, helping to balance estrogen activity within
the body.
Thompson learned flaxseed lignans had been shown to be
protective at the early promotional stage when cancers have not quite formed.
She then wanted to determine whether supplementation with flaxseed, beginning
13 weeks after carcinogen administration, would reduce the size of already
established mammary tumors present at the start of treatment, as well as
appearance of new tumors. After seven weeks of treatment, established tumor
volume was over 50 percent smaller in all treatment groups while there was no
change in the placebo group. This study demonstrated that reduction in tumor
size was due in part to the lignans derived from flaxseed.
In a case-control study from the Queen Elizabeth II
Medical Center, Perth, Western Australia, women with newly-diagnosed, early
breast cancer were interviewed by means of questionnaires, and a 72 hour urine
collection and blood sample were taken. The urine samples were assayed for
various plant constituents including lignans. It was determined that there is a
substantial reduction in breast-cancer risk among women with a high intake of
phyto-oestrogens, particularly the isoflavonic phyto-oestrogen equol and the
lignan enterolactone.
To appreciate the
dual protective effect of lignans and flaxseed oil, it is imperative that
consumers recognize and purchase the right products. Look for flaxseed oil
products that are labeled as high-lignan. Flaxseed oil should be gently
expeller pressed without filtration or refinement.
Case-control
study of phyto-oestrogens and breast cancer.
https://www.ncbi.nlm.nih.gov/pubmed/9329514
October
1997
There is a substantial reduction in breast-cancer risk
among women with a high intake (as measured by excretion) of
phyto-oestrogens-particularly the isoflavonic phyto-oestrogen equol and the
lignan enterolactone. These findings could be important in the prevention of
breast cancer.
