Forum Discussion
saffygirl
4 years agoMember
Letrozole(Femara) +Zoledronic Acid (Zometa)
I am to start 5yrs of Letrozole(daily pill) and Zoledronic Acid (6 monthly intravenous) in a few weeks. The side effect sheets make for crappy reading as usual and am keen to hear anyone's experience...
AllyJay
4 years agoMember
I've been on letrozole since mid 2017 and although I don't have the Zolendronic Acid, I do have a Prolia injection every six months for osteoporosis. I was osteoporotic even before starting the letrozole but it has not become any worse over the past five years, which it would have done without the prolia, even if I wasn't taking the letrozole. I have other medical conditions which cause me big problems with my joints, tendons and muscles, (also skin, blood vessels, kidneys and more), however I'm commenting on the joint, muscle and tendon situation for myself. I can only say that these issues for me have not become worse than either my rheumatologist or myself would have expected five years down the line with my autoimmune condition, even taking the letrozole. I believe that had I not already had these problems, I would have had little problem in this regard. I have had some thinning of my hair and vaginal dryness but am managing with these issues. The only problems I've had with the prolia is that I get a headache for two or three days after I have it, other than that, no problems.