Hi Tennille, I've been on Letrozole for 1 year now. From the beginning I have suffered from the hots sweats and bone pain. I think I mainly get the bone pain when I'm over tired, run down or about to get sick with a cold or something. I take ibuprofen & panadol osteo to dull the pain & wait it out. The sweats are everyday & night. The worse ones are those that start with a feeling of anxiousness, fortunately I only get these once or twice a week. Can't do much for the sweats but keep a fan handy & refuse to go anywhere without airconditioning! But I do think either I'm coping better with them now or they have lessened over the last 6 months. I don't suffer from fatigue now but I did when I first started but I put it down to still recovering from chemo, radiation & the fact my body was a wreck. Take care, Jane