Hi all, As in my above reply, I thought I was doing much better but oh so tired. I just have to look at a job and feel tired. Jenny and Josie, being on the same potion, do you two have bad sinus issues. I blow blood clots out of my nose (yes grose) all day every day. And the headaches are such a pain. My head even aches when I am lying down tender to touch. Is this the same with you two? As soon as the nurses start the Cyclophosphamide drip I feel the sinus starting. Would be interested to know if I am a freak or others have the same. XLeoniePS I feel so tired that I have begged my husband to come with me for my last chemo on Thursday.