@FLClover I looked at the results from Europe and US on Desloratidine and the ‘p-Value’ was 0.001. I had no idea so asked my pharmacist uncle and biochemist friend. The p Value is whether the drug in the test was the reason it worked or if other things came into play, like chance. A p-Value of less than 0.05 is considered to be the drug is what caused the result. Desloratidine was 0.001 so they are pushing for more research. The other antihistamines didn’t come out as well. Desloratidine is sold as Aerius or just Desloratidine generic. My immunologist told me to give it a go. I find it useless as an antihistamine so have to take others as well for Mast Cell activation, but he said just to add it to the others.