Thanks @socoda, I have actually been taking daily loratadine from the beginning as I developed hives then a persistent rash after the first fec chemo, maybe that explains why the Neulasta hasn't been to bad for me until I had it with the dosetaxol. I had my echo today. I have to go back in to onc on Friday now for 3 immunoglobulin injections as it seems I was exposed to measles while I was in hospital and even though I'm immunised, I am severely neutropaenic so that's just what I need right now hey! And guess what? One of the side effects of the inj is bone and muscle pain! Just great