Hi @eastmum -as you can see there are many different reactions to AC. I didn't do well on it and it had to be stopped after 3 cycles as I ended up in hospital with neutropenia. I felt pretty ill most of the time on it but others have found it ok. However I was a bit high on the dex they give you and had no trouble driving home! What I have found is that I react really strongly to each of the chemo drugs but I am reassured that there are others to try. After Paklitakel which gave me hand and feet neuropathy after the first dose! Xeloda has been much better. After some complications with hand and feet! ( see what I mean) the dose is now adjusted and am tolerating much better than other drugs. Hope all goes ok for you. Like others I learnt to roll with it and take it day at a time and learning to really accept living in the moment -knowing even when a bad day or days come there are also good ones around the corner. Wishing you the best.