Hi Chanel, after I had a lumpectomy back in 2003 I started on Tamoxifen and I took it for many years without any problems. I have a fatty, funny liver which was playing up a bit so after about 8 years my oncologist and I decided to stop Tamoxifen to help my liver a bit. I understand I will never know if Tamoxifen was having a negative effect on my liver or if it was my liver being naughty regardless of it. After almost 10 years of my initial diagnosis I developed secondary breast cancer. It's now almost 4 years after that second diagnosis and I'm fine and still doing very well. A hug for you.