Hey Di! Im so sorry to hear about your Mum! I lost mine 8yrs ago so its very difficult. I also had a recurrence, in the same breast at the 4yr mark, and like you in between my yearly checkup, from clear to Stage 2, grade 3 IDC hmmm. I was on Tamoxifen at the time, were you taking anything? recent studies have shown that it only works in 1/3 of cases that it has found a way around Tamoxifen in some women. My Oncologist recently suggests this is what happened to me. I am now on Arimidex all be it having a break for 6 weeks as side effects are crap!! and Im so much better off it! so he may switch to something else. Im recovering from a left breast mastectomy/Diep Flap recon as didnt want to gamble again with that breast. My Mum was the only family history, nothing more, BRCA Gene negative and ER+ so recommendation was not for a double as was unnecessary. Been a 6yr journey for me and have been clear nearly 2yrs, my pathology of the breast was also clear. ITs crap!!! a recurrence when you do all the right things. So sending a hug as I found it more overwhelming 2nd time. Melinda xo