As one of those who worked throughout, please remember that I did not fight my way to work through fatigue and feeling ill. I actually felt fine! I went off my food (no nausea, just not hungry) for a day or two, and I had some problems with really sore feet towards the end of taxol but that was about all that affected normal day to day living. I never needed nausea medication. There was nothing super-human, just luck. So don't make the wrong comparisons, most people feel lousy!! As far as possible, you should do what you need. Most people find there is a cycle, and once they know what it is, a great deal of chemo fear and uncertainty is reduced. Best wishes.