Forum Discussion
Afraser
8 years agoMember
I have been on letrozole (Femara) for over 4 years. Two major side effects are severe vaginal dryness and, as mentioned by Romla, letrozole can weigh in severely on bone density. My bone density was very good before I began so I think I'll get through OK but the vaginal dryness affects your sex life and requires a lot of artificial lubrication or adapting your sex life or both! Not everyone gets the same effects or to the same extent. There are a couple of threads on this topic. There is of course a potential benefit which is why I persist!