Good luck for tomorrow. I managed relatively well on A/C - I had no nausea or fatigue, just lost my appetite entirely for the first two or three days, then recovered. I did find some changes to my sense of taste, inclufing a rather metallic taste. Lost my hair but wasn't offered the scalp cooling cap nearly five years ago. Don't know if I would have tried it or not. My hair went 15 days after my first treatment - it felt really weird for a week before and I had it cut really short before it fell and then wore a wig. I chose to work throughout but it's really hard to know how you will be affected till you have done the first couple of cycles. A/C can be very hard to take for many and if there is a way of working out what makes the difference, I never found it! Seems pretty random. So good luck. Either way you are on your way with treatment, and that's a positive step.