All just depends. I started out being able to exercise on AC from 2nd and 3rd week up until Cycle 3 where I got exhausted. ..then improved a bit cycle 4. On taxol started out okay but progressively got more and more tired and terrible leg pain, some neuropathy and balance issues. The last 2 weeks was spent on a lounge chair. Even now 7 weeks on I couldn't do 5km. I can't manage more than 15 mins. You just have to do what you can when you can. Some weeks are good and others are not. Remember though, we do need some energy reserve for cell recovery. Best of luck. Kath x