@Twiggyjumps and @Zoffiel I am interested in your comments about docetaxel. I am starting chemo shortly (docetaxel and cyclophosphamide) and I have a lot of arthritis in my neck with 2 bulging discs. I also have lumbar spine issues from a car accident. I required physio weekly for my neck. I am now concerned that the docetaxel might make these existing conditions worse (and they are a bit difficult to handle as they are especially at work) and just to top it all off I am allergic to Tramal! Can I ask you both how long your courses of docetaxel were for? Many thanks. I am so sorry to hear of your skeletal issues the pain is just plain horrible.