Tamoxifen and endometrial hyperplasia

Dory65
Dory65 Member Posts: 323 ✭
edited November 2020 in General discussion
Hi Team,
Has anyone else developed endometrial hyperplasia as a side effect of Tamoxifen?
Tagged:

Comments

  • iserbrown
    iserbrown Member Posts: 5,729 ✭
    Yep
  • Michele B
    Michele B Member Posts: 136 ✭
    Hi @Dory65, I developed hyperplasia 3 times in three years while on Tamoxifen. After the third hysteroscopy and curette, my gynae advised me to change hormone treatment. I then went on Arimidex . Im sure one of your team will advise you on the best course to take. You may be lucky and it may only happen once . Best of luck 
    Michele
  • Greengirl
    Greengirl Member Posts: 57 ✭
    I developed super heavy periods with Tamoxifen and am awaiting biopsy results after hysteroscopy etc.
  • ddon
    ddon Member Posts: 349 ✭
    Just a question - how do you know there’s a problem? Are you having bleeding or is it picked up on scans? I am 5 months into tamoxifen and am just wondering what to look out for?
  • iserbrown
    iserbrown Member Posts: 5,729 ✭
    For me, a bleed!
    My GP sent me for a vaginal ultrasound and from there my Medical Oncologist referred me to a Gynaecology Oncologist - and so it is I have regular visits and vaginal ultrasounds.  Now under control but still review and monitoring!
  • Dory65
    Dory65 Member Posts: 323 ✭
    I had non-stop thin watery bloody discharge while on Tamoxifen. I'm now on the public patient waiting list for hysteroscopy and biopsies under general anaesthetic. Just wondering about the whole thing, and how worried I should be, or not. Oncologist has me on Zoladex and Letrozole, which also have their fun side effects.
  • iserbrown
    iserbrown Member Posts: 5,729 ✭
    I've had two hysteroscopy and 2 years of Zoladex injections to shrink the ovaries. 
  • ddon
    ddon Member Posts: 349 ✭
    Thanks for your replies. I haven’t had any strange vaginal discharge or any bleeding as yet. Good to know what to watch for. 
  • Dory65
    Dory65 Member Posts: 323 ✭
    I hope I don't have to have more hysteroscopies. One under general anaesthetic seems quite enough to me. @iserbrown, was a hysterectomy and or oophorectomy ever discussed? Am I naive to think it would be better than monitoring and scanxiety?
  • Blister
    Blister Member Posts: 65 ✭
    Just asking as this is one of my treatment options being discussed at the moment, will definitely be checking this with my specialist, I’m post menopausal and have uterine polyps.

    Has anyone been prescribe Tamoxifen who have already been diagnosed with uterine polyps?
  • iserbrown
    iserbrown Member Posts: 5,729 ✭
    @Blister
    Sending you a private message 
  • Dory65
    Dory65 Member Posts: 323 ✭
    Hi @Blister,
    I don't know the answer re surgical removal vs Zoladex in postmenopausal/post-child-bearing years. It's a question I regret I did not ask the gynecologist who is doing my hysteroscopy. I will ask at the next opportunity. I hope iserbrown was able to help.

Categories